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The purpose of this review is to provide a state-of-the-art translational approach to arterial stiffness, highlighting unique pathophysiological mechanisms (e.g., perivascular adipose tissue (PVAT), extracellular vesicles), clinical relevance, and future directions

The cGAS/STING pathway plays a key role in the chronic inflammatory network by activating NF-B and NLRP3 to promote the production of multiple inflammatory factors (162)

Group E received IV saline once weekly and L-carnitine at a dose of 300 mg/kg, i.p., five times per week for three weeks

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A 0.5mL syringe has its measurement markings more spread out, making it much easier to accurately measure small volumes